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United Therapeutics (UTHR) wins patent ruling against Liquidia (LQDA): UTHR +12.6%, LQDA -57%

What happened

U.S. District Judge Richard G. Andrews (Delaware) ruled Wednesday afternoon that rival Liquidia infringed claims 1 and 14 of United Therapeutics' U.S. Patent No. 11,826,327 — covering inhaled treprostinil for pulmonary hypertension associated with interstitial lung disease (PH-ILD), including dry-powder delivery — while invalidating the four other claims United had asserted. The judge ordered both sides to file proposed final judgments and remedies within one week; United has already sought an injunction that could restrict Yutrepia sales. Stocks diverged sharply: United Therapeutics jumped 12.6% to $541.89 (near its 52-week high of $596.76), Liquidia collapsed 57.2% to $30.26, and MannKind, partnered with United on Tyvaso, popped 16.8%. Leerink Partners analyst Roanna Ruiz called the ruling 'a positive upside surprise for UTHR.' Liquidia CEO Roger Jeffs said the company disagrees and will 'pursue all available appellate options.'

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Who’s affected

  • United Therapeutics (UTHR, +12.6% to $541.89, retaking its 21/50/200-day lines) — Tyvaso franchise protected from dry-powder competition. Liquidia (LQDA, -57.2% to $30.26, worst day ever, undercutting its 200-day average) — faces potential removal of its PH-ILD indication or broader sales curbs. MannKind (MNKD, +16.8%), which is partnered with United on Tyvaso. Specialty biotech/pharma (XBI) — a sharp reminder of Hatch-Waxman patent risk for drug companies.
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Smart Money Hub · build Oct 9, 2026, 2:02 PM EDT